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济源市祛痣多少钱

2019年02月16日 13:40:23|来源:国际在线|编辑:家庭医生社区
One of the leading researchers in the field of protein folding is David Baker of the University of Washington, in Seattle.西雅图华盛顿大学的David Baker是蛋白质折叠领域研究者的领军人物之一。For the past 20 years he and his colleagues have used increasingly sophisticated versions of a program they call Rosetta to generate various possible shapes for a given protein, and then work out which is most stable and thus most likely to be the real one.在过去的20年中,他的团队应利用越来越复杂的“Rosetta”程序,模拟出给定蛋白质的各种可能结构,然后研究对比哪一种结构最稳定并最接近于真正的蛋白质结构。In 2015 they predicted the structures of representative members of 58 of the missing protein families.2015年他们预测了58个未知蛋白质家族成员的代表结构。Last month they followed that up by predicting 614 more.就在1月份他们已预测出614多种蛋白质结构。Even a small protein can fold up into tens of thousands of shapes that are more or less stable.仅仅一个小的蛋白质也能折叠出数以千计的较为稳定的结构。According to Dr Baker, a chain a mere 70 amino acids long—a tiddler in biological terms—has to be folded virtually inside a computer about 100,000 times in order to cover all the possibilities and thus find the optimum.Baker士表示,一条仅70个氨基酸长度的链,在生物界如同一个小孩儿,而想要找到所有的可能性并确定最佳结构需要在电脑中虚拟折叠近10万次。Since it takes a standard microprocessor ten minutes to do the computations needed for a single one of these virtual foldings, even for a protein this small, the project has, for more than a decade, relied on cadging processing power from thousands of privately owned PCs.由于完成仅一个如此小的蛋白质的虚拟折叠便需标准微处理器计算耗时10分钟,故这个项目在十多年来一直借助于上千台个人电脑的处理能力。Volunteers download a version of Dr Baker’s program, called rosetta@home, that runs in the background when a computer is otherwise idle.志愿者可以下载rosetta@home,这是Baker士的程序,当电脑闲置时可让其在后台运行。This “citizen science” has helped a lot.“全民科研”的作用很大。But the real breakthrough, which led to those 672 novel structures, is a shortcut known as protein-contact prediction.但真正的突破性进展是一个被称为蛋白质-接触预测的捷径,使得科学家发现了672个新的蛋白质结构。This relies on the observation that chain-folding patterns seen in nature bring certain pairs of amino acids close together predictably enough for the fact to be used in the virtual-folding process.这得益于在链-折叠模式的自然状态下,观察到了特定的氨基酸对会被拉近在一起的现象,其可预测性足以用于虚拟折叠进程。An amino acid has four arms, each connected to a central carbon atom.一个氨基酸有4条链,每连接一个中心碳原子。Two arms are the amine group and the acid group that give the molecule its name.其中有2条链是用于分子命名的胺基和酸根。Protein chains form because amine groups and acid groups like to react together and link up.蛋白质会互相连接是因为胺基遇到酸根,易反应并连接在一起。The third is a single hydrogen atom.第3条链只有一个氢原子。But the fourth can be any combination of atoms able to bond with the central carbon atom.任何能和中心碳原子相连的任意原子组合,都能与第四条链相连接。It is this fourth arm, called the side chain, which gives each type of amino acid its individual characteristics.这第4条链叫做侧链,赋予每种类型的氨基酸各自的性质。考研英语时事阅读 /201704/503710Thats nice.Nice way to start the day or late night.真不错 这样开始一天或深夜不错啊Because its very late at night right now.We dont tape early.Play along.现在其实是太晚了 我们不会提早录制节目 配合一下嘛So much to talk about.I really love your movie.They got me a copy of your movie and I watched it.有很多可聊 我很喜欢你的新片 他们给了我一份 我看过了I went in not konwing anything and I really loved the story.Cool.我之前不知道剧情 我很喜欢这个故事 酷You won essentially the French version of the Oscar for playing this role,which I think is absolutely amazing.Cesar award,right?Yeah.你因为对这个角色的诠释 赢得了法国版的奥斯卡 我觉得这很棒 凯撒奖 对吗 对First of all,thats got to be an amazing achievement.首先 这是一项了不起的成就You went to the French Oscars,French award show which I think must be very strange.你去了法国奥斯卡颁奖礼 法国的颁奖礼 我想那感觉一定很奇怪I watched some of it and the whole thing is in French,as it should be.因为我看了一点 整个颁奖礼说的都是法语 本来也应该这样And I wouldnt known what the hell was going on.How did you even know what was happening?我都不知道发生了什么 你怎么知道你获奖的Yeah,I went into a meditative state for that period of time.是的 那段时间我基本上入定了It was really long,4 1/2 hour show or something and they dont have advertisements or commercials in France the way we do那颁奖礼很长 大概有四个半小时吧 而且法国和我们不同 他们不会进广告So we didnt even get to take a break and chat and go to the bathroom and get a drink.That usually happens.所以我们没机会休息 聊天 去洗手间 或者喝酒 通常在颁奖礼大家会这样Award shows in America what people watching at home dont realize whenever you go to a commercial,all of the celebrities run all of the room and start drinking like fish.在家的观众对美国颁奖礼不了解的一点是 每当进广告时 所有明星都离开大厅 像鱼一样大口喝酒And then they all rush back in and sit there.Out of their minds.But really happy.Yeah,really happy.然后他们鱼贯而入 坐在那里 全都晕乎乎的 但是非常高兴 对 非常高兴201611/480979

What are you going to do to further improve your English? 你以后将做什么来提高你的英语?除了日常的英语课程以外我相信还有很多办法能够帮助我们更深一层地来提高英语。跟大家分享一位网友的plan:1. I will review what is learnt and preview what will be learnt in class just as I have done in the past.我会review去复习已经学过的知识。Review就是复习的意思:Before the examination we have a review of the terms work. 考试之前,我们复习一学期的功课。同时呢还要preview 预习。说到这里要跟大家说一些词汇的知识。View本身呢就是“见解、视野”的意思,也就是要用眼睛去看的东西。那么前缀re-有重复的含义,review也就是重复地去看,自然也就是复习,而前缀pre则有预先这样的含义,预先地去看preview那也就是预习了。Please do the preview and review work. 请做好预习和复习的工作。温故而知新,是一个非常好的学习习惯。2. English Corner is a good place for me to practice my oral English and I decide to visit there more frequently.英语角是一个锻炼口语的好去处a good place to practice oral English。拿深圳举例,我去过一些免费的英语角,每周六下午5点到7点会有一些人聚集在一起用英语聊天,开始水平可能不怎么样,但是要想提高口语就一定要开口说,不要怕说错,because the first thing is to make people understand you, then try to express yourself well. 先让别人懂你说的意思,等到到了这个水平,再多花些功夫去把语法什么的描述正确。还要提到一个词,frequent-频繁的,经常的,比如说:My girlfriend writes frequent letters to me. 我的女朋友频繁地给我写信。其实我想关注的是这位男士有没有同样去reply frequently频繁地回复呢?Frequent是形容词,而frequently就是副词。English Corner is a good place for me to practice my oral English and I decide to visit there more frequently. 英语角对于我来说呢是一个锻炼口语的好去处,我决定常去那儿瞧瞧。3. I will try to keep a diary about what I and what I experience to practice writing.这位网友还分享说她会把每天所读到的和所经历的都有写日记的方式记录下来,这样就可以练习写作。Thats true. 的确如此。Try to do sth. 尽力去做某事,keep a diary写日记。有朋友可能会问try to do 和try doing有什么区别?这两个短语他们的含义是有些不同的。try to do意思是“努力去做某事”“尽力干…”,表示想尽一切办法要把事情办成。比如:Im trying to learn English well. 我决心(尽力)学好英语。 Try doing意思是“尝试着干某事”“试着(用什么方法)去做某事”,表示一种试着、做做看的做法。试比较:I tried knocking at the back door, but nobody answered. 我试着敲了敲后门,但没人回答。今天给大家分享了一些关于英语学习小小的tips,其实我个人还有一些小方法,比如说对于经常记不住的单词,我就会把他们放在PPT里,然后设置成电脑桌面,这样每次打开电脑就再复习一次。还有一个tip就是在路上一个走的时候自己用英语跟自己对话,这样也是锻炼到口语的。Ok,今天跟大家分享的就是这么多了,其实英语学习也并不难,关键是要培养起对他的兴趣,然后找到适合你自己的方法。希望今天的学习对你有所启发,本期节目就是这样了,感谢收听,再见!背景音乐:喜欢你(英文版)- 杨宇本节目属 /201601/420887

第一, 迷你对话A: Do you have the face to blame me?你还好意思来指责我?B: Why not?为什么不行?A: Look at what you have done.看看你做的好事情。B: None of your business.不管你的事。第二, 地道表达have the face to do sth.1. 解词释义Have the face to do sth.表示“竟敢厚颜,胆敢做某事”“有脸做某事”“ 恬不知耻地(干某事)”等意思。2. 拓展范例e.g. I dont know how you have the face to do such a thing.我真不知道你怎么能如此厚颜,做出这种事来。e.g. How can you have the face to ask for more money when you do so little work?你干这麽少工作还有脸多要钱?e.g. I dont know how you have the face to criticize other people.我真不懂你怎会厚着脸皮去批评别人。 /201611/475855

批评的话恐怕没有几个人爱听,万一说的不合适,吵起来也有可能。但是,工作真的做的不好的时候,该批评还是得批评。其实,批评也是门艺术。如何在批评的同时又不得罪人,今天我们就一起好好来研究研究。Avoid direct accusationsPhrases like “You’re wrong!” and “Your presentation was terrible!” have no place in effective criticism. In fact, it’s best to leave the word “you” out, if at all possible. Personal attacks make people feel defensive, and then they won’t really listen to anything you have to say. 避免正面指责一些表达的方式像是”You’re wrong!”及”Your presentation was terrible!”皆不是有效的批评。事实上,如果可能的话,舍去“你”这个字。个人攻击将使人们会使人自我防御,然后他们将不会听进去你说的任何话。 Soften with complimentsBefore starting with the criticism, warm the person up with compliments. If you are discussing their work, find several things you truly like about what they have done. For example, “I enjoyed your presentation today. You presented a lot of good and helpful information in it, and I can tell you put a lot of effort into it. I appreciate your hard work.” This will lower their defenses and make them feel appreciated. 说些和蔼赞美的话在给予批评以前,先说一些赞美的话给对方暖身暖身。如果你正在探讨他人的工作,找一些你真的喜欢他们所做过的事。例如:”I enjoyed your presentation today. You presented a lot of good and helpful information in it, and I can tell you put a lot of effort into it. I appreciate your hard work.”这将减少他们的防卫自己并让他们有欣慰之意。 Don’t continue with “but”However, a short, vague compliment followed by “but” such as “It was a helpful talk, but you really need to improve your presentation skills” won’t do much to help the process. After you’ve shared your compliments, allow them time to be absorbed. Immediately following your compliment with a “but” will destroy all you’ve tried to accomplish by making your praise seem false and insincere. 切勿使用’but不管如何,由一些’but’的简短模糊赞美,将对于事情不会有太大的帮助。在你已经分享你的赞美之后,允许他们有吸收它的时间。立刻接着马上 /201208/196245

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