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上饶县中医院激光去斑多少钱

2019年02月19日 19:41:35    日报  参与评论()人

上饶县注射丰下巴费用上饶余干县鼻翼整形多少钱This is Florida, a taste of the tropical, one of the worlds most popular holiday destinations. Here mankinds unquenchable desire to explore and colonise reaches astronomical proportions. 这里是弗罗里达,一个充满热带风情的地方,同时也是世界上最著名的度假胜地之一。这里带给人们无法克制的探索和无穷的征欲望。Eight, seven, six, five, four, three, two, one. Ignition. Lift off.八、七、六、五、四、三、二、一。点火,发射。And yet we are relative newcomers here. While other creatures roamed this part of North America for hundreds of millennia, we only arrived at the end of the last great ice age, 13,000 years ago. For most of its existence, North America remained untouched by humans, its dramatic landscapes and wild life undisturbed. Then some time around 13,000 years ago, just as the ice started to relax its grip, hunters from the north set foot in Florida for the first time. Imagine if we could go back and join them as they explore this unknown land, encountering strange animals not seen before by human eyes.然而在这里,我们还只能算是初来乍到。其他生物已经在北美的这块土地徘徊了数十万年,而我们在13000年前的大冰河时期末期来到这里。对大多数存在的生物,北美仍是人类未及之地。这里风景优美,野生动物未受打扰的生活着。约在13000年以前,冰川开始渐渐化去,猎人从北而来,第一次涉足弗洛里达。想象一下,如果时间倒退,我们将追随者猎人的足迹,探寻这未知之地,遇见人类从未见过的奇异的生物。英文文本来自普特英语,译文属.201307/247621上饶治疗腋臭多少钱 上饶铅山县绣眉多少钱

上饶脱毛Don:Hey, Yale. Would you rather be bitten by a saber-toothed tiger or a modern day tiger?唐:嘿,雅艾尔。你宁愿被剑齿虎咬还是被现代的老虎咬?Yael:Neither, of course. But if I have to pick, I supposed I choose the modern tiger. Since the saber-toothed tiger massive fangs.雅艾尔:都不愿意。如果一定要选的话,我情愿选现代的老虎。因为剑齿虎长有巨大的獠牙。Don:Well, you may be surprised to learn that paleontologists now think that despite their huge, fearsome looking canine teeth, the prehistoric American sabercat, Smilodon fatalis, had a bite force only about one-third as strong as modern big cats.唐:不过,古生物学家认为除了巨大的、长相可怕的犬齿之外,美国史前剑齿虎 Smilodon fatalis 的咬合力只有现代大猫的三分之一,知道这一点你可能会觉得很惊讶。Yael:How can they told that from fossilized bones?雅艾尔:他们是如何根据骨头化石得知咬合力的?Don:They used very fine CT scans of the skull, jaw and neck bones to create a highly detailed 3 D computer model. Then using careful analysis of the size and placement of muscle attachment points and mathematical modeling they were able to calculate the power of the jaw muscles and the bite force of the now extinct sabercats. This was the most detailed computer model ever created for a vertebrate.唐:他们用精密的CT扫描仪扫描头骨,颚和颈椎骨,用来建立一个高度精确的3D电脑模型。然后仔细分析肌肉附着点的尺寸和位置,利用这些数据进行数学建模,这样他们才能够计算出目前已经灭绝的剑齿虎的颚肌的力量和咬合力。这是人们迄今建立的最精确的脊椎动物电脑模型。Yael:Neat! So if they had such a wimpy bite, whats with the huge fangs?雅艾尔:做得好!那么如果它们的咬合力小,那么这些獠牙还有何用?Don:The function of the sabercats eight inch teeth is one of the longest running debates in paleontology. The results of this study support the hypothesis that the sabercats brought down and subdued large prey, like mammoths, with their strong forelimbs. Once the prey was safely restrained on the ground, sabercats used their large fangs to pierce through the thick hide on the neck of their quarry. In contrast, modern day big cats use their more powerful jaws to bite the neck of their prey for an extended period to subdue them by asphyxiation.唐:剑齿虎的门牙有八英尺长,至于它的作用至今仍是古生物学届最持久的争议话题之一。这项研究的结果持这种假说:剑齿虎使用强壮的前肢扑倒和制像猛犸象这样的大型猎物。一旦猎物被彻底制在地上,剑齿虎便用它那巨大的獠牙刺穿猎物脖子上的厚皮。相反,现代的大猫则利用更锋利的颚来长时间咬住猎物的脖子,直到它们窒息而亡。Yael:Yikes!I think Ill pass on being bitten by either a sabercat or a modern day tiger.雅艾尔:呀!我想在剑齿虎或者现代老虎咬我的时候,我就会不行了。Don:Wise choice.唐:明智的选择。原文译文属!201304/233270江西上饶市做眼角除皱手术多少钱 Finance and Economics;The euro zones rescue fund; Funny money, fuzzy maths;财经;欧元区救助基金;不明的财源,模糊的数字;The IMFs coffers are fuller, but the euro zones “firewall” is still flimsy;IMF金库充盈,欧元防火墙依旧薄弱;Christine Lagarde, the IMFs managing director, boasted of a “Washington moment”. At its spring meetings in theAmerican capital this month, the fund saw its lending power almost double,thanks to the promise of 430 billion dollar in loans from more than a score of itsmembers. The official goal is to boost a “global firewall” against crisis. Theunofficial hope is that a fatter IMF will help ease fears about the euro, bybolstering the 700 billion euro(925 billion dollar) that euro-zone economies havepledged in their own rescue funds.IMF总裁克丽丝汀·拉嘉德女士骄傲地宣称“华盛顿时刻”已经实现。IMF春季会议于本月在华盛顿召开,20多个成员国的注资承诺使IMF可贷资金规模几乎扩大一倍,增加4300亿美元以上。IMF的官方目标是推动建立“全球防火墙”以摆脱经济危机。私下则希望一个资金充足的IMF可以通过扩从欧元区救助基金来缓和欧洲的恐慌情绪,目前该基金放贷规模已达到7000亿欧元(约合9250亿美元)。Europeans often simplyadd the two numbers together, implying there is now a vast 1.4 trillion dollar stash.Not so. Look behind the fat figures and you find a lot of fuzzy maths andwishful thinking—just as worsening news in Spain brings talk of that countryneeding a rescue (see article).欧洲人总是简单地将这两项金额相加,认为现在欧洲拥有高达1.4万亿的储备资金。事实并非如此。重新审视这个巨额数字,我们会发现大量模糊的数字和一厢情愿的想法——看看西班牙就明白了,不断恶化的局势下,人们纷纷讨论政府是否需要外部救助。Start with the IMF. Assuming countries make good ontheir pledges, the money itself is real. The biggest collectivecontribution will come from the euro-zone countries, which have promised tolend the fund 200 billion dollar between them. Japan is the biggest single donor, with a 60billion dollar pledge motivated partly by a desire not to be eclipsed by China, partlyby fears about its own economic vulnerability. Big emerging economies, such as China, Russiaand Brazil,agreed to chip in. Their contribution, and that of others such as Britain, will be contingent on reforms to thefunds governance, which reduce Europes cloutand increase that of emerging economies. (America, notably, did notcontribute.)我们从IMF开始分析 。假如注资国家兑现他们的承诺,资金可以到位。那么最大的捐赠团体为欧元区国家,他们允诺向IMF注资2000亿欧元;而日本以高达600亿美元的注资抢得头,之所以如此大方,一方面是日本不想被中国的光芒所掩盖,另一方面也表现出对其国内经济脆弱性的担忧。像中国、俄罗斯和巴西这样的新兴经济体也表示了捐助意愿。这些国家(包括英国等国)的注资金额将视IMF的治理改革情况而定,他们希望提升自己在IMF的份额和影响力。值得注意的是,美国表示不会增资IMF。Barring a big fight over its governance, the fund should be flushersoon. But no one wants to write a blank cheque forthe rich euro zone. Canada(which itself did not contribute) called for a double lock: future IMF lendingto the euro zone would need to be approved by a vote among non-Europeanmembers. That probably will not happen, but the fund, at best, will be aminority contributor to future rescues.若果不因治理方式改革而引起成员国的纷争,IMF的钱包将很快鼓起来。可是没有哪个国家愿意给富裕的欧元区开出空白票。加拿大(已经表示拒绝注资)呼吁建立双保险机制:未来IMF向欧元区借款应该取得非欧洲成员国的同意。这难以实现,但至少会使IMF不会充当未来救助工作的“冤大头So the big bucks will have to come from Europesown rescue funds. And they are scantier than they seem. Both the EFSF (theexisting rescue facility) and the ESM (a new permanent fund) need to raiseresources by issuing debt. The EFSF backs its bonds withguarantees from the dwindling number of AAA-rated governments; the ESM willhave some paid-in capital. But both could find it hard to raise the large sumsthat might be required for, say, a swift bank recapitalisation in Spain.由此看出,这一大笔钱只能由欧元区自己的救助基金出,而这些救助基金比我们想象的更缺钱。欧洲金融稳定基金(EFSF,一个已经存在的救助基金)和欧洲稳定机制(ESM,一个新成立的永久性基金)都只能通过发行债券来募集资金。EFSF依靠信用评级为AAA级别的国家的担保来持债券发行,可是欧元区拥有AAA信用评级的国家越来越少;而ESM将会拥有一些实收资本。可是,这两个基金在面对巨额资金需求时(比如西班牙面临的资本迅速重整)都显得力不从心。So speculation is growing that the funds would not bother withhard cash. One idea is for Spainto have a system-wide asset-protection scheme, where the banks toxic assetswould be insured by euro-zone guarantees. Another is for the rescue funds toissue bonds to Spainsown bank-rescue fund, just as the EFSF gave Greek bondholders a bond instead ofcash as part of that countrys debt restructuring.越来越多人猜测这些基金并不用为现金烦恼。一种办法是,西班牙应当建立系统范围的资产保护机制,在该机制下欧元区可为不良资产提供担保。另一种办法是,由救助基金直接向西班牙的救助基金发行债券,正如EFSF向希腊政府债券持有者出售新的债券而不是用现金清偿债务,这也是希腊债务重组的一部分。Another problem is that both the IMF and ESM are considered“preferred creditors”, which means any borrowing from them is first in line forrepayment. If rescue money is sent to the Spanish government to prop up itsbanks, those same banks holdings of government bonds may be worth less. A bigrescue could actually end up reducing confidence. The newly thickened firewallis less solid than it appears.还有一个问题就是IMF和ESM都被看做是优先债权人,这意味着这意味着任何从他们那里得到的借款都必须优先偿还。如果将救助金注入西班牙政府救来帮助其撑本国,其他持有的政府债券很可能贬值。大规模的救助行动很可能最终以削弱市场信心告终。这道新加固的欧洲防火墙并不像看上去那样坚固。 /201305/240663江西省上饶韩美医院祛疤痕多少钱

上饶有没有能治疗毛囊角化症 Business商业报道Biotechnology生物科技Fever rising持续升温There are reasons to hope that the latest biotech boom will not be followed by another bust 我们有理由相信此次生物技术的繁荣不会伴随一次衰退 AS INVESTORS and executives crammed into a New York ballroom for a conference held this week by the Biotechnology Industry Organisation, the mood was jittery.本周,生物科技产业组织举行了一场投资者大会,当业界投资人和高管鱼贯进入舞厅充当的会场时,气氛颇为紧张。The previous week eight biotech firms had launched initial public offerings in America, together raising more than 500m.就在上周,有八家生物技术公司在美国上市,募集的资金总和超过一亿美元。In a discussion panel on whether the industrys latest boom will last, a prominent investor, Oleg Nodelman, joked that he still had suitcases of cash for any firm that wanted it. 在一个关于此次生物科技产业的热潮是否会延续的小组讨论中,知名投资人奥列格?诺德曼开玩笑说:如果还有哪家公司需要资金,我这还有几皮箱现钞可以供应。 Biotechnology is the creation of drugs and other useful products by making use of natures toolkit—that is, by adapting or exploiting processes found in living organisms.生物技术是一种使用自然的工具箱,即通过来改造或利用生物体内的过程来创造药物及其他有用产品的技术;For example, Argos Therapeutics, one of the latest batch of firms to raise money, is working on ways to trigger patients own immune systems to fight kidney cancer or HIV infection. 比如说,最近上市的众多生物技术公司中的Argos Therapeutics,现在正在研究的通过激活患者自身的免疫系统来治疗肾癌和艾滋病的疗法。The industry has undergone cycles of boom and bust since its inception in the 1970s, pioneered by firms such as Genentech.由基因泰克等公司开创于上世纪70年代的生物技术产业自从其建立以来就不断经历繁荣与衰退的循环。As the chart shows, last year more biotech firms joined American stock markets, raising more money, than at any time since the golden year of 2000.如上图所示,自2000年以来,去年是美国生物技术公司上市最多、募集资金总额最多的一年。在In the past 12 months, even as the Samp;P 500 share index has risen by 20%, shares in biotech firms have surged by almost three times as much. 过去的12个月中,尽管标准普尔500股票指数已经上涨了20%,生物技术公司的股价飙升幅度还是有其三倍之多。 One of the main causes for the millennial boom was that investors, flush with money they had made from internet firms, became excited about the Human Genome Project.千禧年生物技术股市繁荣的一个重要原因是,在互联网行业赚得盆满钵满的投资者们对人类基因组计划感到兴奋不已。They hoped that this massive, government-backed effort to lay out the entire genetic code of Homo sapiens would lead to a proliferation of profitable new treatments.他们希望这项由政府持的,旨在铺陈出现代人类整个遗传密码的宏伟工程能够催生出海量有利可图的新疗法。Biotechs flowering is taking some time, however. Biology is complex.但是,生物学是很复杂的,药物搞不好不是毒性太大就是疗效不佳。Drugs have a habit of being too toxic or not working as well as they should. 生物技术的开花结果往往需要很长时间。 Indeed, creating new drugs through biotechnology is at the risky end of a business in which superhuman stamina and bottomless pockets are minimum requirements.事实上,通过生物技术制造新药物是风险最大的行业,超人的耐力和充裕的资金只是最低要求。The Boston Consulting Group reckons that 90% of the money spent researching new treatments, conventional or biotech, goes on drugs that ultimately fail.据波士顿咨询公司估计,用于研制新药的资金,有90%都打了水漂。把之前的试错的损失算在内,After spending as much as 2 billion, accounting for all the failures, a company just might have a medicine that works.一个公司在花了20亿美元后,则有可能获得一种有效的药物。But then it must win the favour of the worlds most stringent regulators, and convince governments, insurers and patients that the drug is worth paying for. 然后你还必须通过世界上最严格的监管程序,最后还要费尽心思向政府、保险公司和患者推销你的药物。 Overcome these obstacles, however, and the returns can be fabulous.然而,在克层层磨难后,得到的回报会高得难以置信。Stelios Papadopolous, a veteran biotech investor, argues that much of the recent rise in share prices is due not to froth, but because the industry is beginning to deliver promising treatments.以为生物科技界的资深投资人斯特里奥斯帕帕多普洛斯认为最近该行业股价的上升大多不是泡沫引起的,而是因为有一批有前途的新疗法开始涌现。In December Americas Food and Drug Administration approved Sovaldi, a treatment for hepatitis C.去年12月,美国食品和药物批准了治疗丙型肝炎的药物Sovaldi,It could now earn revenues of more than 3 billion this year for its maker, Gilead, a biotech firm from California.这项药物今年可为其制造者,加里福利亚州的吉利德公司创造30亿美元的营收。Biogen Idec, a firm based in Massachusetts, is expected to earn more than 1 billion a year from Tecfidera, a pill for multiple sclerosis that the FDA approved last year. The firms shares rose by almost 90% in 2013.百健艾迪一家是总部位于马萨诸塞州的制药公司,有望凭借其去年通过FDA审查的治疗多发性硬化症的小药丸每年盈利10亿美元。But the question is whether such triumphs are aberrations or hints of other victories yet to come. 去年,百健艾迪在的股价上涨了接近90%。但问题是,这些公司的成功究竟底是个例,还是生物技术领域整体繁荣的前兆。 There are several reasons to hope that even if the current share-price and IPO frenzy subsides, biotech firms will continue to prosper.有几点理由能让我们认为即使现在生物技术行业的股价开始下降,IPO狂潮开始平息,生物技术公司依然会继续勇往直前。First, many smaller firms have become the research engines for bigger ones, explains Kevin Starr of Third Rock, a venture-capital firm.首先,三石风险投资公司的凯文?斯塔尔解释称,如今很多小型公司已经变身为大公司的研发引擎。For example Sanofi, a French pharmaceutical giant, now depends on Regeneron, an American biotech company, to help drive its growth.比如说现在的法国制药业巨头赛诺菲,现在依靠美国的生物技术公司Regeneron来推动自身的发展。This year alone, Sanofi will pump about 1 billion into Regenerons research programme.单单今年,赛诺菲就向Regeneron的研发计划注入了10亿美金。The goal is not to Sanofise Regeneron or any other partner, says Christopher Viehbacher, Sanofis chief executive.我们的目的并不是将Regeneron或我们其他的合作伙伴赛诺菲化。Rather, it is to combine Regenerons capabilities in researching new treatments with Sanofis skill in bringing them to market. 赛诺菲得的首席执行官解释说,而是将Regeneron的研发能力和赛诺菲将信品导入市场的能力结合起来。 Celgene, one of Americas larger biotech firms, has a similar distributed model of research. It helps finance the scientific work at smaller companies, then usually takes over a drugs development as it moves into clinical trials.塞尔基因公司,美国的一家大型生物技术公司在研发环节同样使用这种分包模式。Besides being costly, these require expertise that younger, smaller firms often lack. 它先是资助小公司的研发工作,然后在药物开发进入到临床试验阶段是接手,因为此阶段的开发不仅费用高,而且要求小公司缺乏的专门技能。 Second—and more important—firms are at last starting to reap the rewards of studying the human genome.第二点,也是更重要的一点,生物技术公司终于开始在人类基因组的研究上有所斩获。As researchers illuminate the underlying genetic causes of a disease, they open up new routes to developing treatments.一旦研究人员弄清导致一项疾病隐蔽的遗传学原因,就同时为此疾病的治疗提供了一种新途径。For example, Vertex has a drug to treat a subset of patients with cystic fibrosis, thanks to a better understanding of the faulty gene that causes it.比如说福泰制药公司有一种可以治疗患有囊胞性纤维病的特定人群的药物,就是得益于对导致这一疾病的缺陷基因更好的理解。Bluebird bio, one of Celgenes small partner firms, which Third Rock also financed, is working on a treatment for sickle-cell disease that inserts into the patients blood cells a properly functioning version of the faulty gene that causes the inherited ailment. 又比如塞尔基因的一个合作公司蓝鸟生物,同样也是三石风投投资的公司,现在正致力于一种治疗镰状细胞病的疗法:把造成此种遗传疾病的缺陷基因的校正后再插入患者的干细胞内。 Advances in genomics are making clinical trials smaller and cheaper, since it is now easier to identify which patients have the specific genetic trait that a new drug is aimed at.基因组学的发展史的临床试验的规模更小和成本更低,因为现在若要确甄别出具有试验药物针对的那种特定遗传学特征的患者变得更加容易了。This makes it more worthwhile to research diseases that are rare, and those that have so far proved intractable.这样就使得那些对经被罕见的和一直被认为难以治愈的疾病的研究变得更有价值了。The FDA gives special consideration to drugs that treat such ailments, so companies can expect a speedier path to approval. FDA对治疗这类疾病的药物会给予特殊的考虑,所以制药公司会有望快速拿到批准。 Learning from mistakes 吸取经验教训The venture capitalists who back biotech firms are trying to avoid the mistakes they made in the past.投资生物技术的风投家们也正努力避免以前犯过的错误。Index Ventures, based in Geneva, does not shower companies with cash to build lavish headquarters.总部位于日内瓦的指数创投没有挥金如土去盖奢华的总部大楼,Instead it assembles a tiny team of scientists and executives to oversee the research on a promising new line of treatment, outsourcing the bulk of the work to external contractors.而是召集一个有科学家和高管组成的小组来监控有前景的新疗法的研发,并把大部分的工作外包出去。This makes the costs more predictable. It also makes it easier for Index to halt a project when it looks like failing. 这样不仅使得成本更具可预见性,也能方便指数创投叫停可能失败的项目。 Despite all these reasons for optimism, there is no guarantee that the current boom will last.尽管有这么多令人乐观的理由,我们不能肯定这次的繁荣会一直持续。In these sunny times, it is tempting to forget the dark days that companies have endured.快乐的日子总是会诱使人忘却曾让你备受煎熬的黑暗往事。Twenty-five years later, quips Leonard Schleifer of Regeneron, Im an overnight success.我等了25年,Regenron的CEO莱纳德?施莱弗尔自嘲道,我终于一夜暴富了。It is also uncertain that insurers and governments will continue to pay biotech firms high prices.我们同样不能确定保险公司和政府是否会继续高价购买生物技术公司的产品。Vertexs treatment for cystic fibrosis costs a staggering 294,000 for each course. 福泰制药的治疗囊胞性纤维症的药物疗程的费用就高达骇人的294,000美金。 The most important question is whether research has indeed become more productive.最重要的问题是,我们不知道生物科技领域的研究工作是否真的变得极富成效。More than 80% of those recently polled by Mark Schoenebaum, an analyst at ISI Group, said yes.国际战略投资集团的分析师Mark Schoenebaum在调查了80%的生物科技公司后,得出的是肯定的。Mr Schoenebaum himself, however, is unconvinced. Im not arguing definitively that it hasnt happened, he muses, but I havent been entirely persuaded.但他本人却对此结果存疑。我不是否认这一结果,Schoenebaum沉思道,我只是没有被完全说。There are no data yet, he says, to draw firm conclusions. And for all the advances in genomics, and the increased sophistication of biotech firms and their investors, there is still a lot of luck involved in Ramp;D.尽管基因组学取得长足进步,生物技术公司与其投资者的经验也在不断增长,但医药研发极富不确定性的情况不会改变。 /201402/276031上饶韩美整形美容医院切眼袋好吗上饶市人民医院整形美容科

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